Cytophagic histiocytic panniculitis: A diagnostic challenge
نویسندگان
چکیده
Cytophagic histiocytic panniculitis (CHP) was first described in 1980. It classically presents with intermittent recurrent episodes of pyrexia subcutaneous nodules, pancytopenia and liver dysfunction, but most patients have in addition a multitude of other manifestations which confuse the clinical picture. Despite the variable clinical course, the disease is often fatal. Diagnosis is based on histological features. A lobular panniculitis with an infiltrate of cytologically benign cytophagocytic histiocytes in skin nodules is indispensable for establishing the correct diagnosis. We report case of CHP occurring in a 52-year-old male. Correspondence: Dr. Nabeel Najem MD, Department of Dermatology, Adan Hospital, Kuwait, Email: [email protected] Cytophagic histiocytic panniculitis
منابع مشابه
[Histiocytic cytophagic panniculitis].
UNLABELLED A HISTOPATHOLOGICAL DIAGNOSIS: Histiocytic cytophagic panniculitis is the specific skin finding in the reactive hemophagocytic syndrome. It is a feverish nodular eruption which accompanies the other clinical and biological features of the reactive hemophagocytic syndrome. Histopathologic changes are diagnostic and consist in a lobular panniculitis characterized by the presence of a h...
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A 33 year old man developed fever, malaise, jaundice, pancytopenia, coagulation abnormalities, hepatomegaly, pleural effusions and a subcutaneous lump. Biopsies revealed a lobular panniculitis with the presence of cytophagic histiocytes; erythrophagocytosis was also demonstrated in the liver and bone marrow. Despite the use of chemotherapy (CHOP) his clinical condition deteriorated and he died ...
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